Sert Tablets Usage And Safety
Dosage
Sertraline HCl
Side Effects
Hypersensitivity reactions to sertraline , Disulfiram-alcohol reaction when ZOLOFT oral solution is taken with disulfiram , QT prolongation and ventricular arrhythmias when taken with pimozide , Suicidal thoughts and behaviors , Serotonin syndrome , Increased risk of bleeding , Activation of mania/hypomania , Discontinuation syndrome , Seizures , Angle-closure glaucoma , Hyponatremia.
Drug Interactions
Selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue , other SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John?s Wort, aspirin, clopidogrel, heparin, warfarin , propafenone, flecainide, atomoxetine, desipramine, dextromethorphan, metoprolol, nebivolol, perphenazine, thoridazine, tolterodine, venlafaxine , fosphenytoin .
Indication
Sertraline HCl is indicated for the treatment of the following *Major depressive disorder (MDD) * Obsessive-compulsive disorder (OCD) * Panic disorder (PD)
When not to Use
It is contraindicated in patients:-Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome.- Taking pimozide- With known hypersensitivity to sertraline (e.g., anaphylaxis, angioedema).