Adoxa Tablets Usage And Safety
Dosage
Doxycycline (as Hyclate)
Side Effects
? Sensitivity to sunlight – you may get a skin rash, itching, redness or severe sunburn when out in sunlight or after using a sun bed (Photosensitivity reaction) ? Increased pressure in the skull (severe headaches, blurred and/or double vision, blind spots, permanent loss of vision) (Peripheral oedema) ? Headache ? Low blood pressure (Hypotension) ? Nausea/vomiting ? Rashes (consisting of flat or raised red, brown or pink lesions) ? Inflammation of small blood vessels (Henoch-Schonlein purpura) ? Hives (Urticaria) ? Increased heart rate (Tachycardia) ? Shortness of breath or breathlessness (Dyspnoea) ? Blood disorders (symptoms may include tiredness, weakness, easy bruising or susceptibility to infection) ? The Jarisch-Herxheimer reaction which causes fever, chills, headache, muscle pain and skin rash that is usually self-limiting. This occurs shortly after starting doxycycline treatment for infections with spirochete such as Lyme disease. ? Porphyria (sensitivity of the skin to sunlight, inflammation of nerves and stomach pains) ? Discolouration of thyroid tissue (does not affect thyroid function) ? Decreased appetite ? Bulging fontanelles (soft spot on head) of infants ? Anxiety ? Flushing ? Pancreatitis (manifested by severe upper abdominal pain).
Drug Interactions
Penicillin antibiotics , Rifampicin , warfarin , Quinapril , Oral contraceptives , Phenobarbital , Carbamazepine, phenytoin, primidone , Ciclosporin , Methoxyflurane , Methotrexate , antacids (indigestion tablets or liquids) containing aluminium, calcium, magnesium or other medicines containing iron, bismuth or zinc salts , Retinoids .
Indication
It is used to treat a wide range of infections caused by bacteria, these include: ? Chest, lung or nasal infections e.g. bronchitis, pneumonia, sinusitis ? Infections of the kidneys and bladder e.g. cystitis, urethritis ? Infections of the skin such as acne ? Eye infections ? Sexually transmitted diseases e.g. gonorrhoea, syphilis, chlamydia ? Rickettsial infections such as Q fever or fevers associated with louse or tick bites ? Malaria, when chloroquine is not effective ? Other infections such as cholera, brucellosis, leptospirosis and psittacosis
When not to Use
Hypersensitive to any of the ingredients in the list.
