Zylexx Sr Usage And Safety
Dosage
Bupropion HCl
Side Effects
Agitation, dry mouth, insomnia, headache/migraine, nausea/vomiting, constipation, and tremor, taste disorders, dizziness, concentration disturbances.
Drug Interactions
Inhibitors/inducers of the CYP2B6 isoenzyme (e.g., orphenadrine, thiotepa, cyclophosphamide, ticlopidine, and clopidogrel) , paroxetine, sertraline, norfluoxetine, and fluvoxamine as well as nelfinavir and efavirenz , antidepressants (SSRIs, many tricyclics), beta-blockers, antiarrhythmics, and antipsychotics , nortriptyline, imipramine, desipramine, antipsychotics e.g., haloperidol, risperidone, thioridazine , beta-blockers (e.g., metoprolol), antiarrhythmics e.g., propafenone, flecainide , MAO Inhibitors , Levodopa and Amantadine , antipsychotics, other antidepressants, theophylline, systemic steroids, Alcohol.
Indication
It is indicated for the treatment of major depressive episodes.
When not to Use
It is contraindicated in patients with hypersensitivity to bupropion or any of the excipients , In patients with a current seizure disorder or any history of seizures , In patients with a known central nervous system tumour.