Avsar Tablets Usage And Safety
Dosage
Amlodipine Besilate + Valsartan
Side Effects
Nasopharyngitis, influenza, hypokalemia, headache, asthenia, fatigue, facial edema, flushing, hot flush, edema, edema peripheral and pitting edema , Anorexia, hypercalcemia, hyperlipidemia, hyperuricemia, hyponatremia, coordination abnormal, dizziness, dizziness postural, paraesthesia, somnolence, visual impairment, vertigo, palpitations, tachycardia, orthostatic hypotension, cough, pharyngolaryngeal pain, abdominal discomfort, abdominal pain upper, constipation, diarrhea, dry mouth, nausea, erythema, rash, arthralgia, back pain and joint swelling.
Drug Interactions
Antihypertensive agents , grapefruit or grapefruit juice , CYP3A4 inhibitors (protease inhibitors, azole antifungals, macrolides like erythromycin or clarithromycin, verapamil or diltiazem) , CYP3A4 inducers (e.g. rifampicin, Hypericum perforatum) , Simvastatin , Lithium , Potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium , NSAIDs , (rifampicin, cyclosporine) or efflux transporter (ritonavir) , Sildenafil.
Indication
It is indicated for the treatment of Hypertension.
When not to Use
The combination of amlodipine and valsartan is contraindicated in: – Patients with known hypersensitivity to the active substances, to dihydropyridine derivatives or to any of the excipient of the product. Severe hepatic impairment, biliary cirrhosis or cholestasis.