Betnesol Tablets Usage And Safety
Dosage
Betamethasone
Side Effects
Prolonged treatment with corticosteroids in high dosage is occasionally associated with subcapsular cataract, skin thinning, osteoporosis, and glaucoma. In addition, any of the features of hypercortisolism, such as suppression of the HPA axis, may occur. Aseptic osteonecrosis, particularly of the femoral head, may occur after prolonged corticosteroid therapy or after repeated short courses involving high dosage.
Drug Interactions
Live vaccines or other vaccines , anticoagulants , hypoglycaemia agents , antihypertensives , diuretics , erythromycin , rifamycin , amphotericin , azole antifungals , ritonavir , cyclosporin , cardiac glycosides . Oestrogens including oral contraceptives , somatropin . Carbamazepine , phenytoin , primidone , barbiturates . Muscle relaxants , NSAIDs, salicylates , sympathomimetics , mifepristone , methotrexate , theophylline , aprepitant .
Indication
A wide variety of diseases may sometimes require corticosteroid therapy. Some of the principalindications are: ? Bronchial asthma. ? Severe hypersensitivity reactions – Anaphylaxis. ? Rheumatoid arthritis. ? Systemic lupus erythematosus. ? Dermatomyositis. ? Mixed connective tissue disease (excluding systemic sclerosis). ? Polyarteritis nodosa. ? Inflammatory skin disorders including pemphigus vulgaris, bullous pemphigoid, and Pyoderma gangrenosum. ? Minimal change nephrotic syndrome
When not to Use
? Systemic infections, unless specific anti-infective therapy is employed. ? Live virus immunisation. ? Hypersensitivity to any component .