Combivair Rotacaps Usage And Safety
Dosage
?Formoterol Fumarate, Budesonide?
Side Effects
Common Candida infections in the oropharynx, headache, tremor, palpitations, mild irritation in the throat, coughing and hoarseness. Uncommon Aggression, psychomotor hyperactivity, anxiety, sleep disorders, dizziness, tachycardia, nausea, bruises and muscle cramps. Rare Immediate and delayed hypersensitivity reactions, e.g. exanthema, urticaria, pruritus, dermatitis, angioedema and anaphylactic reaction, hypokalemia, cardiac arrhythmias, e.g. atrial fibrillation, supraventricular tachycardia, extrasystoles and bronchospasm. Very Rare Cushing’s syndrome, adrenal suppression, growth retardation, decrease in bone mineral density, hyperglycemia, depression, behavioural changes, taste disturbances, cataract, glaucoma, angina pectoris, prolongation of QTC-interval and variations in blood pressure
Drug Interactions
Potent inhibitors of CYP3A4 (e.g., ketoconazole, itraconazole, voriconazole, posaconazole, clarithromycin, telithromycin, nefazodone and HIV protease inhibitors) , ? blockers (including eye drops) , Concomitant treatment with quinidine, disopyramide, procainamide, phenothiazines and tricyclic antidepressants , L-Dopa, L-thyroxine, oxytocin and alcohol , monoamine oxidase inhibitors or tricyclic antidepressants,non-potassium-sparing diuretics (such as loop or thiazide diuretics).
Indication
It is indicated for the treatment of Asthma , Maintenance Treatment of Chronic Obstructive Pulmonary Disease (COPD).
When not to Use
Budesonide + Formoterol is contraindicated: – In patients with known hypersensitivity to Budesonide or Formoterol or to any excipient of the product. – In primary treatment of status asthmaticus or other acute episodes of asthma or COPD where intensive measures are required.
