Coversyl Plus Usage And Safety
Dosage
Perindopril, Indapamide
Side Effects
Severe dizziness or fainting due to low blood pressure (Common – may affect up to 1 in 10 people), – Bronchospasm (tightening of the chest, wheezing and shortness of breath (Uncommon) (may affect up to 1 in 100 people), – Swelling of the face, lips, mouth, tongue or throat, difficulty in breathing (angioedema) , (Uncommon-may affect up to 1 in 100 people), – Severe skin reactions including erythema multiforme (a skin rash which often starts with red itchy patches on your face, arms or legs) or intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (Stevens Johnson Syndrome) or other allergic reactions. (Very rare-may affect up to 1 in 10,000 people)- Cardiovascular disorders (irregular heart beat, angina pectoris (pains to the chest, jaw and back, brought on by physical effort),( heart attack) – Weakness of arms or legs, or problems speaking which could be a sign of a possible stroke- Inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell – Yellowing of the skin or eyes (jaundice) which could be a sign of hepatitis- Life-threatening irregular beat.(Not known) – Disease of the brain caused by liver illness (Hepatic encephalopathy) (Not known).
Drug Interactions
Lithium , aliskiren , potassium-sparing diuretics (e.g. triamterene, amiloride), potassium salts, trimethoprim/sulfamethoxazole) , estramustine , racecadotril , (sirolimus, everolimus, temsirolimus , moxifloxacin, sparfloxacin , methadone , procainamide , allopurinol , mizolastine, terfenadine or astemizole , halofantrine , pentamidine , vincamine , bepridil , quinidine, hydroquinidine, disopyramide, amiodarone, sotalol , cisapride, diphemanil , baclofen , insulin, metformin or gliptins , amphotericin B , g. tricyclic antidepressants, neuroleptics (such as amisulpride, sulpiride, sultopride, tiapride, haloperidol, droperidol , ephedrine, noradrenaline or adrenaline.
Indication
It is used in the treatment of high blood pressure (hypertension) in adults.
When not to Use
Do not take Perindopril/Indapamide If you are allergic to perindopril or any other ACE inhibitor, or to indapamide or any other sulphonamides or any of the other ingredients of this medicine , – if you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren, – if you have severe liver disease or suffer from a condition called hepatic encephalopathy (degenerative disease of the brain), – if you have a severe kidney disease where the blood supply to your kidneys is reduced (renal artery stenosis).