Ezita Tablets Usage And Safety
Dosage
Ezetimibe
Side Effects
Body as a whole: Fatigue ; Gastrointestinal system disorders: Abdominal pain, diarrhea ; Infection and infestations: Infection viral, pharyngitis, sinusitis ; Musculo-skeletal system disorders: Arthralgia, back pain ; Respiratory system disorders: Cough
Drug Interactions
Gemfibrozil , Antacids , Cholestyramine , Fibrates , Cyclosporine .
Indication
Ezetimibe is indicated: As adjunctive therapy to diet for the reduction of elevated total-C, LDLC, and Apo B in patients with primary (heterozygous familial and nonfamilial) hypercholesterolemia as monotherapy or as combination therapy with HMG-CoA reductase inhibitors. In combination with atorvastatin or simvastatin to reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other non-pharmacological or lipid lowering treatments (e.g. LDL apheresis) or if such treatments are unavailable or inadequate ; As adjunctive therapy to diet for the reduction of elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia.
When not to Use
Ezetimibe is contraindicated in patients with hypersensitivity to ezetimibe or any component of the product. Ezetimibe in combination with an HMG-CoA reductase inhibitor is contraindicated in patients with active liver disease or unexplained persistent elevations in serum transaminases.