Hcq Tablets Usage And Safety
Dosage
Hydroxychloroquine?Sulphate
Side Effects
The side-effects of hydroxychloroquine includes gastro-intestinal disturbances, headache and skin reactions (rashes, pruritus); those occurring less frequently include convulsions, visual changes, keratopathy, ototoxicity, hair depigmentation, hair loss and discoloration of skin, nails, and mucous membranes. In rare cases, hydroxychloroquine has caused visual changes or loss of vision. Side-effects that occur rarely include blood disorders (including thrombocytopenia, agranulocytosis and aplastic anemia), mental changes (including emotional disturbances and psychosis), myopathy, (including cardiomyopathy and neuromyopathy), acute generalized exanthematous pustulosis, exfoliative dermatitis, Stevens-Johnson syndrome, photosensitivity and hepatic damage, angioedema has also been reported.
Drug Interactions
Alfa and Beta Agalsidase , Laronidase , Amiodarone , Droperidol , Moxifloxacin , Antacids , Kaolin , Lanthanum , Antiepileptic , Mefloquine , Ciclosporin , Digoxin , Cimetidine , Neostigmine , Pyridostigmine .
Indication
Hydroxychloroquine sulfate is indicated for the treatment of: * Active rheumatoid arthritis (including juvenile idiopathic arthritis). * Systemic and discoid lupus erythematosus. *Dermatological conditions caused or aggravated by sunlight.
When not to Use
Hydroxychloroquine is contraindicated in: * Patients with known hypersensitivity to 4-aminoquinoline compounds. * Patients with pre-existing maculopathy of the eye. * Long-term therapy in children. * Children under 6 years of age.