-7%

Lowplat Tablets 75Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)

Original price was: Rs.270.8.Current price is: Rs.251.9.

Per Box

SKU: LOWTAB641 Categories: Heart & Blood Pressure, Medicines, Stroke & Paralysis Recovery Brand: Pharmevo Private Limited.

Specifications

Lowplat Tablets Specification
Requires Prescription (YES/NO)

Generics

Clopidogrel

Used For

Stroke

How it works

Clopidogrel is a prodrug, one of whose metabolites is an inhibitor of platelet aggregation. Clopidogrel must be metabolised by CYP450 enzymes to produce the active metabolite that inhibits platelet aggregation. The active metabolite of clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. Due to the irreversible binding, platelets exposed are affected for the remainder of their lifespan (approximately 7-10 days) and recovery of normal platelet function occurs at a rate consistent with platelet turnover. Platelet aggregation induced by agonists other than ADP is also inhibited by blocking the amplification of platelet activation by released ADP.

Usage & Safety

Lowplat Tablets Usage And Safety
Dosage

Clopidogrel

Side Effects

Abdominal pain, dyspepsia, gastritis, diarrhea, nausea, vomiting, constipation, gastrointestinal hemorrhage, ulceration, neutropenia, rash, palpitation, syncope, drowsiness, asthenia, neuralgia, paresthesia and vertigo.

Drug Interactions

Warfarin , Glycoprotein IIb/IIIa inhibitors , Acetylsalicylic acid (ASA) , Heparin , Thrombolytics , NSAIDs , SSRIs , omeprazole and esomeprazole, fluvoxamine, fluoxetine, moclobemide, voriconazole, fluconazole, ticlopidine, carbamazepine, and efavirenz .

Indication

Secondary prevention of atherothrombotic events : Adult patients suffering from myocardial infarction (from a few days until less than 35 days), ischaemic stroke (from 7 days until less than 6 months) or establishedperipheral arterial disease. Prevention of atherothrombotic and thromboembolic events in atrial fibrillation: In adult patients with atrial fibrillation who have at least one risk factor for vascular events, are not suitable for treatment with Vitamin K antagonists (VKA) and who have a low bleeding risk, clopidogrel is indicated in combination with ASA for the prevention of atherothrombotic and thromboembolic events, including stroke.

When not to Use

1.Hypersensitivity to the active substance. 2. Active pathological bleeding such as peptic ulcer or intracranial haemorrhage. 3.Severe hepatic impairment.

Precautions

Lowplat Tablets Precautions
Precaution

Due to the risk of bleeding and haematological adverse reactions, blood cell count determination and/or other appropriate testing should be promptly considered whenever clinical symptoms suggestive of bleeding arise during the course of treatment. Patients should be followed carefully for any signs of bleeding including occult bleeding, especially during the first weeks of treatment and/or after invasive cardiac procedures or surgery.

Warnings

Lowplat Tablets Warnings
Warning 1

Acquired haemophilia: in cases of confirmed isolated activated Partial Thromboplastin Time (aPTT) prolongation with or without bleeding, acquired haemophilia should be considered. Patients with a confirmed diagnosis, clopidogrel should be discontinued.

Warning 2

Recent ischaemic stroke: Clopidogrel cannot be recommended during the first 7 days after acute ischaemic stroke .

Warning 3

Hepatic impairment: Experience is limited in patients with moderate hepatic disease who may have bleeding diatheses. Clopidogrel should therefore be used with caution in this population .

Additional Info

Lowplat Tablets Additional Information
Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.

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Orders below PKR 1500 are subject to a PKR 200 delivery fee.
Orders of PKR 1500 and above qualify for free delivery.
Delivery time is 3-4 days for most areas and within 6 hours in Faisalabad.

5. Return & Refund Policy

Returns are accepted within 3 days of purchase, subject to our Return Policy.
Refunds will be processed within 7-14 working days.

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We are not liable for any indirect, incidental, or consequential damages arising from the use of our services.

8. Medicine Side Effects Policy

We are not responsible for any side effects or adverse reactions caused by the medicines purchased from our store.
Customers are advised to consult a healthcare professional before using any medication.
In case of any adverse reaction, discontinue use immediately and seek medical assistance.

9. Governing Law

These terms are governed by the laws of Pakistan. Any disputes shall be resolved through arbitration or legal proceedings in Pakistan.

10. Changes to Terms & Conditions

We reserve the right to update these Terms & Conditions at any time. Continued use of our website signifies your acceptance of the updated terms.

For any inquiries, contact our customer support team.

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