-7%

Masacol Tablets 800Mg (1 Strip = 10 Tablets)

Original price was: Rs.713.0.Current price is: Rs.663.1.

Per Strip

SKU: MASTAB306 Categories: Irritable Bowel (IBS), Medicines, Stomach & Digestion Brand: Getz Pharma Pakistan

Specifications

Masacol Tablets Specification
Requires Prescription (YES/NO)

Generics

Mesalazine

Used For

Acidity & Ulcers

How it works

Mesalazine has an anti-inflammatory effect through a mechanism that has not yet been fully clarified. Mesalazine inhibits migration of polymorph nuclear leukocytes and lipoxygenase of cells at concentrationsreached in the large intestine during treatment. The production of pro-inflammatory leukotrienes (LTB4 and 5-HETE) in macrophages of the intestinal wall is then inhibited. Mesalazine has been shown to activatePPAR-Y receptors which counteract nuclear activation of intestinal inflammatory responses.

Usage & Safety

Masacol Tablets Usage And Safety
Dosage

Mesalazine

Side Effects

Common : Headache, diarrhea, abdominal pain, nausea, vomiting, rash, drug fever, dizziness, arthralgia and dyspepsiaRare : Myocarditis, pericarditis, anemia, tinnitus, paresthesia, flatulence, pruritus, urticaria, myalgia, interstitial nephritis, myocarditis, pancreatitis, abnormal renal , function, leucopenia, thrombocytopenia, agranulocytosis and neutropenia.

Drug Interactions

Digoxin , Azathioprine and 6-mercaptopurine , furosemide and spironolactone , warfarin , glucocorticoids , NSAIDs, methotrexate.

Indication

Mesalazine is indicated for the treatment of:- Mild to moderate acute exacerbations of ulcerative colitis.- Maintenance of remission of ulcerative colitis.- Maintenance of remission of crohn’s ileo-colitis.

When not to Use

Mesalazine is contraindicated in:? Patients with a history of sensitivity to salicylates.? Patients with severe renal insufficiency.? Patients with severe hepatic insufficiency.? Children under 2 years of age.? Concomitant use of lactulose or similar preparations should be avoided.

Precautions

Masacol Tablets Precautions
Precaution

Patients on oral forms of mesalazine should have renal function monitored with serum creatinine levels measured prior to treatment start, every three months for the first year, then 6 monthly for the next 4 yearsand annually after that. Treatment with mesalazine should be discontinued if renal function deteriorates.

Warnings

Masacol Tablets Warnings
Warning 1

Following mesalazine treatment, serious blood dyscrasias have been reported rarely. If the patient develops unexplained bleeding, hematoma bruising, purpura, anemia, persistent fever or sore throat, hematological investigations should be performed. If there is suspicion of blood dyscrasia, treatment should be terminated.

Warning 2

In case of existing gastric or duodenal ulcers treatment should begin with caution based on theoretical grounds.

Warning 3

Caution should be used in patients with previous myopericarditis of allergic background regardless of its origin.

Additional Info

Masacol Tablets Additional Information
Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.

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Orders below PKR 1500 are subject to a PKR 200 delivery fee.
Orders of PKR 1500 and above qualify for free delivery.
Delivery time is 3-4 days for most areas and within 6 hours in Faisalabad.

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Returns are accepted within 3 days of purchase, subject to our Return Policy.
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We are not responsible for any side effects or adverse reactions caused by the medicines purchased from our store.
Customers are advised to consult a healthcare professional before using any medication.
In case of any adverse reaction, discontinue use immediately and seek medical assistance.

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For any inquiries, contact our customer support team.

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