Paraxyl Tablets Usage And Safety
Dosage
Paroxetine HCl
Side Effects
Abnormal bleeding, predominantly of the skin and mucous membranes (mostly ecchymosis), thrombocytopenia , allergic reactions (including urticaria and angioedema , syndrome of inappropriate anti-diuretic hormone secretion (SIADH) , hyponatraemia , somnolence, insomnia, agitation, abnormal dreams (including nightmares) , confusion, hallucinations , dizziness, tremor, headache.
Drug Interactions
L-tryptophan, triptans, tramadol, SSRIs, lithium, fentanyl and St. John?s Wort ? Hypericum perforatum ? preparations , Pimozide , carbamazepine, rifampicin, phenobarbital, phenytoin , Fosamprenavir , ritonavir , Procyclidine , carbamazepine, phenytoin, sodium valproate , tricyclic antidepressants, phenothiazine neuroleptics, risperidone, atomoxetine, certain Type 1c antiarrhythmics and metoprolol.
Indication
It is indicated for the symptomatic relief of Major Depressive Disorder.
When not to Use
Known hypersensitivity to paroxetine and excepients. Paroxetine should not be used in combination with monoamine oxidase (MAO) inhibitors (including linezolid, an antibiotic which is a reversible non-selective MAO inhibitor) or within 2 weeks of terminating treatment with MAO inhibitors. Likewise, MAO inhibitors should not be introduced within 2 weeks of cessation of therapy with paroxetine.