Sinemet Tablets Usage And Safety
Dosage
Levodopa , Carbidopa
Side Effects
The most common side effects are ? Abnormal movements such as twitching or spasms (which may or may not be like your Parkinson’s symptoms) ? nausea. Other side effects include ? Fainting, anorexia, high blood pressure ? inflammation of the veins, being sick (vomiting), diarrhoea, discoloration of urine, sweat or saliva ? on-off phenomenon, characteristic of some people with long-standing Parkinson?s disease. This is when you can have unpredictable changes from being mobile – ?on? – to a sudden inability to move – ?off?. ?Off? to ?on? can occur just as suddenly. ? dizziness; sleepiness (including excessive drowsiness or sudden sleep onset episodes), pins and needles ? dream abnormalities, confusion, feeling agitated, shortness of breath, hair loss .
Drug Interactions
MAOIs , Anticholinergic medicines such as orphenadrine, trihexyphenidyl, benzatropine and procyclidine , Phenytoin , Papaverine .
Indication
It improves the signs of Parkinson?s disease .
When not to Use
Do not take if: ? You are allergic (hypersensitive) to carbidopa or levodopa or any of the other ingredients in the list ? You have ever had skin cancer or you have any unusual moles which have not been examined by your doctor ? You are taking certain medicines called ?MAOIs? (Monoamine Oxidase Inhibitors) used for depression. You need to stop using these medicines at least two weeks before you start this medicine.