Solifen Tablets Usage And Safety
Dosage
Solifenacin Succinate
Side Effects
Very common Dry mouth.Common Constipation, nausea, dyspepsia, abdominal pain, blurred vision.Uncommon : Gastroesophageal reflux diseases, dry throat, urinary tract infection, cystitis, somnolence, dysgeusia, dry eyes, fatigue, peripheral edema, nasal dryness, dry skin, difficulty in micturation.Rare : Colonic obstruction, fecal impaction, urinary retention.
Drug Interactions
Metoclopramide , cisapride , Ketoconazole and other CYP3A4 Inhibitors , CYP3A4 substrates with higher affinity (e.g., verapamil, diltiazem) and CYP3A4 inducers (e.g., rifampacin, phenytoin, carbamazepin).
Indication
Solifenacin Succinate is indicated for the symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency as may occur in patients with overactive bladder syndrome.
When not to Use
Solifenacin Succinate is contraindicated in patients with: – Hypersensitivity to the active substance or to any of the excipients.- Urinary retention. – Gastric retention.- Uncontrolled narrow-angle glaucoma. – Patients undergoing hemodialysis.- Patients with severe hepatic insufficiency and renal insufficiency . Solifenacin Succinate should not be used in children as safety and efficacy in children have not yet been established.