Zurig Tablets Usage And Safety
Dosage
Febuxostat? ? ?
Side Effects
Common : Headache, diarrhea, nausea, rash and LFT abnormalities.Uncommon : Blood amylase increase, platelet count decrease, blood creatinine increase, hemoglobin decrease, blood urea increase , LDH increase, triglycerides increase, dizziness, paraesthesia, somnolence, altered taste, abdominal pain, gastro-oesophageal reflux disease, vomiting, dry mouth, dyspepsia, constipation, frequent stools, flatulence, gastrointestinal discomfort, nephrolithiasis, hematuria, pollakiuria, dermatitis, urticaria, pruritus, arthralgia, arthritis, myalgia, muscle cramp, musculoskeletal pain, weight increase, increased appetite, hypertension, flushing, hot flush, fatigue, edema, influenza like symptoms and libido decreased. Rare : Palpitations, renal insufficiency, asthenia, thirst, nervousness and insomnia.
Drug Interactions
Naproxen and other inhibitors of glucuronidation , NSAIDs and probenecid , UGT enzymes
Indication
Febuxostat is indicated for the chronic management of hyperuricemia in patients with gout.
When not to Use
Febuxostat is contraindicated in patients with: – Hypersensitivity to the active substance or to any of the excipients of the product. – Being treated with azathioprine, mercaptopurine or theophylline. – Asymptomatic hyperuricemia.
