Zyloric Tablets Usage And Safety
Dosage
Allopurinol
Side Effects
Uncommon (may affect less than 1 in 100 people) : A reaction of any kind such as flaking skin, boils or sore lips and mouth or very rarely, sudden wheeziness, fluttering or tightness in the chest; collapse . Rare (may affect less than 1 in 1000 people) : Fever and chills, headache, aching muscles (flu-like symptoms) and generally feeling unwell , serious hypersensitivity reactions involving fever, skin rash, joint pain, abnormalities in blood and liver function tests (these may be signs of a multi-organ sensitivity disorder). bleeding in the lips, eyes, mouth, nose or genitals, any changes to your skin, for example; ulcers of the mouth, throat, nose, genitals and conjunctivitis (red and swollen eyes), widespread blisters or peeling.
Drug Interactions
Immunosuppressants e.g. 6-mercaptopurine, azathioprine and cyclosporin , adenine arabinoside (vidarabine), other medicines to treat gout, such as probenecid , aspirin (or related drugs called salicylates) , chlorpropamide, used to treat diabetes , drugs which thin the blood (anticoagulants), such as warfarin , medicines used for fits (epilepsy), phenytoin , theophylline, used for breathing problems , antibiotics (ampicillin or amoxicillin) , drugs used for the treatment of cancer , didanosine, used to treat HIV infection , medicines for heart problems or high blood pressure such as ACE inhibitors or water tablets (diuretics) , cyclophosphamide, doxorubicin, bleomycin, procarbazine, alkyl halogenides.
Indication
It is indicated for reducing urate/uric acid formation in conditions where urate/uric acid deposition has already occurred (e.g. gouty arthritis, skin tophi, nephrolithiasis) .
When not to Use
It should not be administered to individuals known to be hypersensitive to allopurinol or to any of the components of the formulation.