Biflor Sachet Usage And Safety
Dosage
Saccharomyces Boulardii
Side Effects
Rare: Fungemia, serious allergic reactions: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Uncommon: Constipation, Flatulence, bloating, increased thirst.
Drug Interactions
Use of systemic antifungals such as fluconazole, itraconazole, terbinafine with S.boulardii supplements causes loss of efficacy of S. boulardii. Concomitant use is not recommended.
Indication
Treatment and prevention of diarrhea, including viral types such as rota-viral diarrhea in children ? Treatment and prevention of diarrhea caused by overgrowth of gastrointestinal bad bacteria or caused by use of antibiotics including Clostridium difficile associated diarrhea (CDAD) and recurring Clostridium difficile associated colitis. ? Treatment of traveler’s diarrhea and diarrhea associated with tube feedings. ? Treatment of diarrhea associated with Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD) including Crohns disease and Ulcerative Colitis, and bacterial overgrowth in Short bowel syndrome .
When not to Use
It should not be used in ? Immunocompromised patients ? GI wall perforation ? Patients allergic to yeast or yeast-based products ? Patients taking systemic antifungals (This will lead to loss of efficacy of S.boulardii) ? Critically ill patients and patients having central venous catheters .