Coversam Tablets Usage And Safety
Dosage
Amlodipine , Perindopril
Side Effects
Very common side effects (may affect more than 1 in 10 people): Edema (Fluid retention). – Common side effects (may affect up to 1 in 10 people): Headache, dizziness, sleepiness (especially at the beginning of treatment), vertigo, numbness or tingling sensation in your limbs, vision disturbances (including double vision), tinnitus (sensation of noises in the ears), palpitations (awareness of your heartbeat), flushing, light-headedness due to low blood pressure, cough, shortness of breath, nausea (feeling sick), vomiting (being sick), abdominal pain, taste disturbances, dyspepsia or difficulty of digestion, change of bowel habit, diarrhoea, constipation, allergic reactions (such as skin rashes, itching), muscle cramps, tiredness, weakness, ankle swelling (oedema peripheral).
Drug Interactions
Aliskiren , diuretics , racecadotril , sirolimus, everolimus, temsirolimus , Sacubitril/valsartan , ibuprofen , insulin , tricyclic antidepressants, antipsychotics, imipramine-like antidepressants, neuroleptics , ciclosporine,tacrolimus , trimethoprim and Co-trimoxazole , allopurinol , procainamide , lithium , estramustine , potassium-sparing drugs (triamterene, amiloride), potassium supplements or potassium-containing salt substitutes , prazosin, alfuzosin, doxazosin, tamsulosin, terazosin, ritonavir, indinavir, nelfinavir , rifampicin, erythromycin, clarithromycin
Indication
It is used for treatment of high blood pressure (hypertension) and/or treatment of stable coronary artery disease (a condition where the blood supply to the heart is reduced or blocked).
When not to Use
Do not take : If you are allergic to perindopril or any other ACE inhibitor, or to amlodipine or any other calcium antagonists, or any of the other ingredients of this medicine , – If you are more than 3 months pregnant , -If you have experienced symptoms such as wheezing, swelling of the face or tongue, intense itching or severe skin rashes with previous ACE inhibitor treatment or if you or a member of your family have had these symptoms in any other circumstances (a condition called angioedema) .